PEPC rabbit pAb
Product Sizes
50UL
£ POA
ES20649-50UL
100UL
£ POA
ES20649-100UL
About this Product
- SKU:
- ES20649
- Additional Names:
- PGC; Gastricsin; Pepsinogen C
- Application:
- Western Blot
- Clonality:
- Polyclonal
- Extra Details:
- This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq; Oct 2009];
- Immunogen:
- Synthetic Peptide of PEPC
- Isotype:
- IgG
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
