LC3A rabbit pAb
Product Sizes
50UL
£ POA
ES20427-50UL
100UL
£ POA
ES20427-100UL
About this Product
- SKU:
- ES20427
- Additional Names:
- Microtubule-associated proteins 1A/1B light chain 3A (Autophagy-related protein LC3 A;Autophagy-related ubiquitin-like modifier LC3 A;MAP1 light chain 3-like protein 1;MAP1A/MAP1B light chain 3 A;MAP1A/MAP1B LC3 A;Microtubule-associated protein 1 light chain 3 alpha)
- Application:
- Western Blot, ELISA, Immunohistochemistry
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- function:Probably involved in formation of autophagosomal vacuoles (autophagosomes).;PTM:The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form; LC3-I. This is activated by APG7L/ATG7; transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form; LC3-II.;similarity:Belongs to the MAP1 LC3 family.;subcellular location:LC3-II binds to the autophagic membranes.;subunit:3 different light chains; LC1; LC2 and LC3; can associate with MAP1A and MAP1B proteins.;tissue specificity:Most abundant in heart; brain; liver; skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.;
- Immunogen:
- Synthesized peptide derived from human LC3A
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
