I-TAC rabbit pAb
Product Sizes
50UL
£ POA
ES20290-50UL
100UL
£ POA
ES20290-100UL
About this Product
- SKU:
- ES20290
- Additional Names:
- C-X-C motif chemokine 11 (Beta-R1;H174;Interferon gamma-inducible protein 9;IP-9;Interferon-inducible T-cell alpha chemoattractant;I-TAC;Small-inducible cytokine B11)
- Application:
- Western Blot, Immunohistochemistry
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- disease:Expressed in a variety of skin disorders; including allergic contact dermatitis; lichen planus and mycosis fungoides.;function:Chemotactic for interleukin-activated T-cells but not unstimulated T-cells; neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.;induction:By interferon gamma and interferon beta. Induction by IFN-gamma is enhanced by TNF-alpha in monocytes; dermal fibroblasts and endothelial cells; and by IL-1 in astrocytes.;mass spectrometry: PubMed:10233762;online information:CXCL11 entry;similarity:Belongs to the intercrine alpha (chemokine CxC) family.;tissue specificity:High levels in peripheral blood leukocytes; pancreas and liver astrocytes. Moderate levels in thymus; spleen and lung. Low levels in placenta; prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders.;
- Immunogen:
- Synthesized peptide derived from human I-TAC AA range: 45-94
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
