BMP-4 rabbit pAb
Product Sizes
50UL
£ POA
ES20285-50UL
100UL
£ POA
ES20285-100UL
About this Product
- SKU:
- ES20285
- Additional Names:
- Bone morphogenetic protein 4 (BMP-4;Bone morphogenetic protein 2B;BMP-2B)
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- disease:Defects in BMP4 are the cause of microphthalmia syndromic type 6 (MCOPS6) [MIM:607932]; also known as microphthalmia and pituitary anomalies or microphthalmia with brain and digit developmental anomalies. Microphthalmia is a clinically heterogeneous disorder of eye formation; ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases; microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities. MCOPS6 is characterized by microphthalmia/anophthalmia associated with facial; genital; skeletal; neurologic and endocrine anomalies.;function:Induces cartilage and bone formation. Also act in mesoderm induction; tooth development; limb formation and fracture repair.;online information:Bone morphogenetic protein 4 entry;similarity:Belongs to the TGF-beta family.;subunit:Homodimer; disulfide-linked (By similarity). Interacts with GREM2 (By similarity) and SOSTDC1. Part of a complex consisting of TWSG1 and CHRD.;tissue specificity:Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues; and prostate cancer cell lines.;
- Immunogen:
- Synthesized peptide derived from human BMP-4 AA range: 261-310
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
