APOB rabbit pAb
Product Sizes
50UL
£ POA
ES20262-50UL
100UL
£ POA
ES20262-100UL
About this Product
- SKU:
- ES20262
- Additional Names:
- Apolipoprotein B-100 (Apo B-100) [Cleaved into: Apolipoprotein B-48 (Apo B-48)]
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms; apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single; very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA); resulting in the creation of a stop codon; and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia; normotriglyceridemic hypobetalipoproteinemia; and hypercholesterolemia due to ligand-defective apoB; diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq; Jul 2008];
- Immunogen:
- Synthesized peptide derived from human APOB
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Type:
- Antibodies: Polyclonal Antibody
