IL1RA rabbit pAb
Product Sizes
50UL
£ POA
ES20257-50UL
100UL
£ POA
ES20257-100UL
About this Product
- SKU:
- ES20257
- Additional Names:
- Interleukin-1 receptor antagonist protein (IL-1RN;IL-1ra;IRAP;ICIL-1RA;IL1 inhibitor;Anakinra)
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- disease:Genetic variation in IL1RN is associated with susceptibility to diabetic nephropathy [MIM:612628]; also called susceptibility to microvascular complications of diabetes type 4 (MVCD4). Diabetic nephropathy is a kidney disease and resultant kidney function impairment due to the long standing effects of diabetes on the microvasculature (glomerulus) of the kidney. Features include increased urine protein and declining kidney function.;function:Inhibits the activity of IL-1 by binding to its receptor. Has no IL-1 like activity.;online information:Interleukin-1 entry;online information:The Singapore human mutation and polymorphism database;pharmaceutical:Available under the name Kineret (Amgen). Used for the reduction in signs and symptoms and slowing the progression of structural damage in moderately to severely active rheumatoid arthritis.;similarity:Belongs to the IL-1 family.;tissue specificity:The intracellular form of IL1RN is predominantly expressed in epithelial cells.;
- Immunogen:
- Synthesized peptide derived from human IL1RA
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
