COL1A2 rabbit pAb
Product Sizes
50UL
£ POA
ES2021-50UL
100UL
£ POA
ES2021-100UL
About this Product
- SKU:
- ES2021
- Additional Names:
- COL1A2; Collagen alpha-2(I) chain; Alpha-2 type I collagen
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone; cornea; dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV; Ehlers-Danlos syndrome type VIIB; recessive Ehlers-Danlos syndrome Classical type; idiopathic osteoporosis; and atypical Marfan syndrome. Symptoms associated with mutations in this gene; however; tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts; resulting from the use of alternate polyadenylation signals; have been identified for this gene. [provided by R. Dalgleish; Feb 2008];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Collagen I alpha2. AA range:471-520
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
