14-3-3σ (Phospho Ser186) rabbit pAb
Product Sizes
50UL
£ POA
ES20196-50UL
100UL
£ POA
ES20196-100UL
About this Product
- SKU:
- ES20196
- Additional Names:
- 14-3-3 protein sigma (Epithelial cell marker protein 1;Stratifin)
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- function:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners; usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17; regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.;function:p53-regulated inhibitor of G2/M progression.;similarity:Belongs to the 14-3-3 family.;subcellular location:May be secreted by a non-classical secretory pathway.;subunit:Homodimer. Interacts with KRT17 (By similarity). Found in a complex with XPO7; EIF4A1; ARHGAP1; VPS26A; VPS29; VPS35 and SFN.;tissue specificity:Present mainly in tissues enriched in stratified squamous keratinising epithelium.;
- Immunogen:
- Synthesized peptide derived from human 14-3-3σ (Phospho Ser186)
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
