CtBP1/2 (Phospho Ser158/164) rabbit pAb
Product Sizes
50UL
£ POA
ES20176-50UL
100UL
£ POA
ES20176-100UL
About this Product
- SKU:
- ES20176
- Additional Names:
- C-terminal-binding protein 1 (CtBP1;EC 1.1.1.-)
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- cofactor:NAD. Required for efficient interaction with E1A. Cofactor binding induces a conformation change.;function:Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex (By similarity). Co-repressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity.;PTM:ADP-ribosylated; when cells are exposed to brefeldin-A (BFA).;PTM:Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4.;PTM:The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylated upon DNA damage; probably by ATM or ATR. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation.;similarity:Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.;subunit:Interacts with the C-terminus of adenovirus E1A protein; ELK3 and CTIP via their consensus motif P-X-[DNS]-L-[STVA]. Can form homodimers or heterodimers of CTBP1 and CTBP2. Interacts with FOXP2; HDAC4; HDAC5 and HDAC9. Interacts with GLIS2 but not GLIS1 or GLIS3 (By similarity). Interacts with FOXP1; HIPK2; PNN and NRIP1. Interacts with ZFHX1B and WIZ. Interacts with Epstein-Barr virus EBNA3 and EBNA6.;
- Immunogen:
- Synthesized peptide derived from human CtBP1/2 (Phospho Ser158/164)
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
