DNA pol β (Acetyl Lys72) rabbit pAb
Product Sizes
50UL
£ POA
ES20123-50UL
100UL
£ POA
ES20123-100UL
About this Product
- SKU:
- ES20123
- Additional Names:
- DNA polymerase beta (EC 2.7.7.7;EC 4.2.99.-)
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).;cofactor:Binds 2 magnesium ions per subunit.;domain:Residues 239-252 form a flexible loop which appears to affect the polymerase fidelity.;function:Repair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.;PTM:Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity.;similarity:Belongs to the DNA polymerase type-X family.;subunit:Monomer.;
- Immunogen:
- Synthesized peptide derived from human DNA pol β (Acetyl Lys72)
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
