Collagen V α1 (Cleaved-Ala1605) rabbit pAb
Product Sizes
50UL
£ POA
ES19976-50UL
100UL
£ POA
ES19976-100UL
About this Product
- SKU:
- ES19976
- Additional Names:
- Collagen alpha-1(V) chain
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- disease:Defects in COL5A1 are a cause of Ehlers-Danlos syndrome type 1 (EDS1) [MIM:130000]; also known as Ehlers-Danlos syndrome gravis or severe classic type Ehlers-Danlos syndrome. EDS is a connective tissue disorder characterized by hyperextensible skin; atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. EDS1 is the severe form of classic Ehlers-Danlos syndrome.;disease:Defects in COL5A1 are a cause of Ehlers-Danlos syndrome type 2 (EDS2) [MIM:130010]; also known as Ehlers-Danlos syndrome mitis or mild classic type Ehlers Danlos syndrome.;function:Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA; heparan sulfate; thrombospondin; heparin; and insulin.;PTM:Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.;PTM:Sulfated on 40% of tyrosines.;similarity:Belongs to the fibrillar collagen family.;similarity:Contains 1 laminin G-like domain.;similarity:Contains 1 TSP N-terminal (TSPN) domain.;subunit:Trimers of two alpha 1(V) and one alpha 2(V) chains in most tissues and trimers of one alpha 1(V); one alpha 2(V); and one alpha 3(V) chains in placenta. Interacts with CSPG4.;
- Immunogen:
- Synthesized peptide derived from human Collagen V α1 (Cleaved-Ala1605)
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
