Collagen I α1 (Cleaved-Ala1218) rabbit pAb
Product Sizes
50UL
£ POA
ES19972-50UL
100UL
£ POA
ES19972-100UL
About this Product
- SKU:
- ES19972
- Additional Names:
- Collagen alpha-1(I) chain (Alpha-1 type I collagen)
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone; cornea; dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV; Ehlers-Danlos syndrome type VIIA; Ehlers-Danlos syndrome Classical type; Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22; where this gene and the gene for platelet-derived growth factor beta are located; are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans; resulting from unregulated expression of the growth factor. Two transcripts; resulting from the use of alternate polyadenylation signals; have been identified for this gene. [provided by R. Dalgleish; Feb 2008];
- Immunogen:
- Synthesized peptide derived from human Collagen I α1 (Cleaved-Ala1218)
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
