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Antibodies

CATB (Cleaved-Leu80) rabbit pAb

Product Sizes
50UL
£ POA
ES19957-50UL
100UL
£ POA
ES19957-100UL
About this Product
SKU:
ES19957
Additional Names:
Cathepsin B (EC 3.4.22.1;APP secretase;APPS;Cathepsin B1) [Cleaved into: Cathepsin B light chain; Cathepsin B heavy chain]
Application:
Western Blot, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
catalytic activity:Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase; shows peptidyl-dipeptidase activity; liberating C-terminal dipeptides.;function:Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.;similarity:Belongs to the peptidase C1 family.;subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.;subunit:Dimer of a heavy chain and a light chain cross-linked by a disulfide bond.;
Immunogen:
Synthesized peptide derived from human CATB (Cleaved-Leu80)
Isotype:
IgG
Reactivities:
Human, Rat, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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