Caspase 4 (p10; Cleaved-Ala290) rabbit pAb
Product Sizes
50UL
£ POA
ES19956-50UL
100UL
£ POA
ES19956-100UL
About this Product
- SKU:
- ES19956
- Additional Names:
- Caspase-4 (CASP-4;EC 3.4.22.57;ICE(rel)-II;Protease ICH-2;Protease TX) [Cleaved into: Caspase-4 subunit 1; Caspase-4 subunit 2]
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- catalytic activity:Strict requirement for Asp at the P1 position. It has a preferred cleavage sequence of Tyr-Val-Ala-Asp-|- but also cleaves at Asp-Glu-Val-Asp-|-.;function:Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves caspase-1.;PTM:The two subunits are derived from the precursor sequence by an autocatalytic mechanism or by cleavage by Caspase-8.;similarity:Belongs to the peptidase C14A family.;similarity:Contains 1 CARD domain.;subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers; each one formed by a small and a large subunit.;tissue specificity:Widely expressed; with highest levels in spleen and lung. Moderate expression in heart and liver; low expression in skeletal muscle; kidney and testis. Not found in the brain.;
- Immunogen:
- Synthesized peptide derived from human Caspase 4 (p10; Cleaved-Ala290)
- Isotype:
- IgG
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
