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Antibodies

CHOP rabbit pAb

Product Sizes
50UL
£ POA
ES1978-50UL
100UL
£ POA
ES1978-100UL
About this Product
SKU:
ES1978
Additional Names:
DDIT3; CHOP; CHOP10; GADD153; DNA damage-inducible transcript 3 protein; DDIT-3; C/EBP-homologous protein; CHOP; C/EBP-homologous protein 10; CHOP-10; Growth arrest and DNA damage-inducible protein GADD153
Application:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members; such as C/EBP and LAP (liver activator protein); and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis; is activated by endoplasmic reticulum stress; and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq; Aug 2010];
Immunogen:
The antiserum was produced against synthesized peptide derived from human CHOP. AA range:15-64
Isotype:
IgG
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Type:
Antibodies: Polyclonal Antibody
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