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Antibodies

Cdk8 rabbit pAb

Product Sizes
50UL
£ POA
ES1944-50UL
100UL
£ POA
ES1944-100UL
About this Product
SKU:
ES1944
Additional Names:
CDK8; Cyclin-dependent kinase 8; Cell division protein kinase 8; Mediator complex subunit CDK8; Mediator of RNA polymerase II transcription subunit CDK8; Protein kinase K35
Application:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
cyclin dependent kinase 8(CDK8) Homo sapiens The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28; and Schizosaccharomyces pombe cdc2; and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex; which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH); thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery. [provided by RefSeq; Jul 2008];
Immunogen:
The antiserum was produced against synthesized peptide derived from human CDK8. AA range:1-50
Isotype:
IgG
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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