CAS rabbit pAb
Product Sizes
50UL
£ POA
ES1844-50UL
100UL
£ POA
ES1844-100UL
About this Product
- SKU:
- ES1844
- Additional Names:
- CSE1L; CAS; XPO2; Exportin-2; Exp2; Cellular apoptosis susceptibility protein; Chromosome segregation 1-like protein; Importin-alpha re-exporter
- Application:
- Western Blot, Immunohistochemistry, Immunoprecipitation, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS; while importin-beta mediates translocation through the nuclear pore complex. After translocation; RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm; leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha; and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition; the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq; Jan 2012];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human CSE1L. AA range:1-50
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
