CARD 11 rabbit pAb
Product Sizes
50UL
£ POA
ES1840-50UL
100UL
£ POA
ES1840-100UL
About this Product
- SKU:
- ES1840
- Additional Names:
- CARD11; CARMA1; Caspase recruitment domain-containing protein 11; CARD-containing MAGUK protein 1; Carma 1
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family; a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family; which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10; a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells; this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq; Jul 2008];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human CARD11. AA range:10-59
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
