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Antibodies

ANO3 rabbit pAb

Product Sizes
50UL
£ POA
ES18338-50UL
100UL
£ POA
ES18338-100UL
About this Product
SKU:
ES18338
Application:
Western Blot
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene belongs to the TMEM16 family of predicted membrane proteins; that are also known as anoctamins. While little is known about the function of this gene; mutations in this gene have been associated with some cases of autosomal dominant craniocervical dystonia. Cells from individuals with a mutation in this gene exhibited abnormalities in endoplasmic reticulum-dependent calcium signaling. Studies in rat show that the rat ortholog of this protein interacts with; and modulates the activity of a sodium-activated potassium channel. Deletion of this gene caused increased pain sensitivity in the rat model system. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq; Aug 2015];
Immunogen:
Synthesized peptide derived from human ANO3 AA range: 518-568
Isotype:
IgG
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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