ARVC rabbit pAb
Product Sizes
50UL
£ POA
ES18243-50UL
100UL
£ POA
ES18243-100UL
About this Product
- SKU:
- ES18243
- Additional Names:
- Armadillo repeat protein deleted in velo-cardio-facial syndrome
- Application:
- Western Blot
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Armadillo Repeat gene deleted in Velo-Cardio-Facial syndrome (ARVCF) is a member of the catenin family. This family plays an important role in the formation of adherens junction complexes; which are thought to facilitate communication between the inside and outside environments of a cell. The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS); a relatively common human disorder with phenotypic features including cleft palate; conotruncal heart defects and facial dysmorphology. The ARVCF gene encodes a protein containing two motifs; a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition; ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein. [provided by RefSeq; Jun 2010];
- Immunogen:
- Synthesized peptide derived from human ARVC AA range: 563-613
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
