ATR (phospho-Thr1989) rabbit pAb
Product Sizes
50UL
£ POA
ES18189-50UL
100UL
£ POA
ES18189-100UL
About this Product
- SKU:
- ES18189
- Additional Names:
- Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1)
- Application:
- Western Blot
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene belongs the PI3/PI4-kinase family; and is most closely related to ATM; a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3; a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1; checkpoint proteins RAD17; and RAD9; as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported; however; its full length nature is not known. Transcript variants utilizing alternative polyA sites exist. [provided by RefSeq; Jul 2008];
- Immunogen:
- Synthesized phosho peptide around human ATR (Thr1989)
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
