BAP1 (phospho-Ser592) rabbit pAb
Product Sizes
50UL
£ POA
ES18098-50UL
100UL
£ POA
ES18098-100UL
About this Product
- SKU:
- ES18098
- Additional Names:
- Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1) (Cerebral protein 6)
- Application:
- Western Blot
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition; the enzyme may be involved in regulation of transcription; regulation of cell cycle and growth; response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS); which involves increased risk of cancers including malignant mesothelioma; uveal melanoma and cutaneous melanoma. [provided by RefSeq; May 2013];
- Immunogen:
- Synthesized phosho peptide around human BAP1 (Ser592)
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
