BBS7 rabbit pAb
Product Sizes
50UL
£ POA
ES18092-50UL
100UL
£ POA
ES18092-100UL
About this Product
- SKU:
- ES18092
- Application:
- Western Blot
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes one of eight proteins that form the BBSome complex containing BBS1; BBS2; BBS4; BBS5; BBS7; BBS8; BBS9 and BBIP10. The BBSome complex is believed to recruit Rab8(GTP) to the primary cilium and promote ciliogenesis. The BBSome complex assembly is mediated by a complex composed of three chaperonin-like BBS proteins (BBS6; BBS10; and BBS12) and CCT/TRiC family chaperonins. Mutations in this gene are implicated in Bardet-Biedl syndrome; a genetic disorder whose symptoms include obesity; retinal degeneration; polydactyly and nephropathy; however; mutations in this gene and the BBS8 gene are thought to play a minor role and mutations in chaperonin-like BBS genes are found to be a major contributor to disease development in a multiethnic Bardet-Biedl syndrome patient population. Two transcript variants encoding distinct isoforms have been identified for this gene.[provided by RefSeq; Oct 2014];
- Immunogen:
- Synthesized peptide derived from human BBS7 AA range: 85-135
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
