Bax rabbit pAb
Product Sizes
50UL
£ POA
ES1753-50UL
100UL
£ POA
ES1753-100UL
About this Product
- SKU:
- ES1753
- Additional Names:
- BAX; BCL2L4; Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by BAX (BCL2 associated X; apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2; and functions as an apoptotic activator. This protein is reported to interact with; and increase the opening of; the mitochondrial voltage-dependent anion channel (VDAC); which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants; which encode different isoforms; have been reported for BAX.
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Bax. AA range:1-50
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
