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Antibodies

CENP-M rabbit pAb

Product Sizes
50UL
£ POA
ES17525-50UL
100UL
£ POA
ES17525-100UL
About this Product
SKU:
ES17525
Additional Names:
Centromere protein M (CENP-M;Interphase centromere complex protein 39;Proliferation-associated nuclear element protein 1)
Application:
Immunohistochemistry, Immunofluorescence, Western Blot
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is an inner protein of the kinetochore; the multi-protein complex that binds spindle microtubules to regulate chromosome segregation during cell division. It belongs to the constitutive centromere-associated network protein group; whose members interact with outer kinetochore proteins and help to maintain centromere identity at each cell division cycle. The protein is structurally related to GTPases but cannot bind guanosine triphosphate. A point mutation that affects interaction with another constitutive centromere-associated network protein; CENP-I; impairs kinetochore assembly and chromosome alignment; suggesting that it is required for kinetochore formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq; Jan 2015];
Immunogen:
Synthesized peptide derived from human CENP-M AA range: 30-110
Isotype:
IgG
Reactivities:
Human, Rat, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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