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Antibodies

DUOX1 rabbit pAb

Product Sizes
50UL
£ POA
ES16881-50UL
100UL
£ POA
ES16881-100UL
About this Product
SKU:
ES16881
Application:
Western Blot
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter; thyroperoxidase; and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase; lactoperoxidase; and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq; Jul 2012];
Immunogen:
Synthesized peptide derived from human DUOX1 AA range: 1398-1448
Isotype:
IgG
Reactivities:
Human, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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