DUS7 rabbit pAb
Product Sizes
50UL
£ POA
ES16877-50UL
100UL
£ POA
ES16877-100UL
About this Product
- SKU:
- ES16877
- Application:
- Western Blot
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs; designated MKPs; that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795); JNK (see MIM 601158); and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes; including cellular proliferation; apoptosis; differentiation; and stress responses (summary by Patterson et al.; 2009 [PubMed 19228121]).[supplied by OMIM; Dec 2009];
- Immunogen:
- Synthesized peptide derived from human DUS7 AA range: 210-260
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
