APC5 rabbit pAb
Product Sizes
50UL
£ POA
ES1676-50UL
100UL
£ POA
ES1676-100UL
About this Product
- SKU:
- ES1676
- Additional Names:
- ANAPC5; APC5; Anaphase-promoting complex subunit 5; APC5; Cyclosome subunit 5
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C); a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b); compared to isoform a. [provided by RefSeq; Nov 2008];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human ANAPC5. AA range:151-200
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
