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Antibodies

APC rabbit pAb

Product Sizes
50UL
£ POA
ES1674-50UL
100UL
£ POA
ES1674-100UL
About this Product
SKU:
ES1674
Additional Names:
APC; DP2.5; Adenomatous polyposis coli protein; Protein APC; Deleted in polyposis 2.5
Application:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion; transcriptional activation; and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP); an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq; Jul 2008];
Immunogen:
The antiserum was produced against synthesized peptide derived from human APC. AA range:2794-2843
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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