F111A rabbit pAb
Product Sizes
50UL
£ POA
ES16638-50UL
100UL
£ POA
ES16638-100UL
About this Product
- SKU:
- ES16638
- Application:
- Western Blot
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is cell-cycle regulated; and has nuclear localization. The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP) box; that is necessary for its co-localization with proliferating cell nuclear antigen (PCNA). Reduced expression of this gene resulted in DNA replication defects; consistent with the demonstrated role for this gene in Simian Virus 40 (SV40) viral replication. Mutations in this gene have been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS; also known as Gracile Bone Dysplasia); both characterized by short stature; hypoparathyroidism; bone development abnormalities; and hypocalcemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq; Aug 2015];
- Immunogen:
- Synthesized peptide derived from human F111A AA range: 264-314
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Type:
- Antibodies: Polyclonal Antibody
