FKBP1A/B rabbit pAb
Product Sizes
50UL
£ POA
ES16393-50UL
100UL
£ POA
ES16393-100UL
About this Product
- SKU:
- ES16393
- Application:
- Immunohistochemistry, Immunofluorescence, Western Blot
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a member of the immunophilin protein family; which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels; and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse; deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants; encoding the same protein; have been identified. The human genome contains five pseudogenes related to this gene; at least one of which is transcribed. [provided b
- Immunogen:
- Synthesized peptide derived from human FKBP1A/B AA range: 26-75
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
