GluR-2 (Phospho-Tyr876) rabbit pAb
Product Sizes
50UL
£ POA
ES16165-50UL
100UL
£ POA
ES16165-100UL
About this Product
- SKU:
- ES16165
- Additional Names:
- Glutamate receptor 2 (GluR-2;AMPA-selective glutamate receptor 2;GluR-B;GluR-K2;Glutamate receptor ionotropic; AMPA 2;GluA2)
- Application:
- Immunohistochemistry, Immunofluorescence, Western Blot
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA); and function as ligand-activated cation channels. These channels are assembled from 4 related subunits; GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain; which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function; and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing; resulting in transcript variants enco
- Immunogen:
- Synthesized peptide derived from human GluR-2 (Phospho-Tyr876)
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
