Actinin-α1/2/3/4 rabbit pAb
Product Sizes
50UL
£ POA
ES1593-50UL
100UL
£ POA
ES1593-100UL
About this Product
- SKU:
- ES1593
- Additional Names:
- ACTN1; Alpha-actinin-1; Alpha-actinin cytoskeletal isoform; F-actin cross-linking protein; Non-muscle alpha-actinin-1; ACTN2; Alpha-actinin-2; Alpha-actinin skeletal muscle isoform 2; F-actin cross-linking protein; ACTN3; Alpha-actinin-3; A
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins; including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells; the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions; where it is involved in binding actin to the membrane. In contrast; skeletal; cardiac; and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies; where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle; cytoskeletal; alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq; Jul 2008];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human ACTN1/2/3/4. AA range:21-70
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
