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Antibodies

EpoR (phospho Tyr426) rabbit pAb

Product Sizes
50UL
£ POA
ES1538-50UL
100UL
£ POA
ES1538-100UL
About this Product
SKU:
ES1538
Additional Names:
EPOR; Erythropoietin receptor; EPO-R
Application:
Western Blot, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding; this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase; phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq; May 2010];
Immunogen:
Synthesized phospho-peptide around the phosphorylation site of human EpoR (phospho Tyr426)
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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