LRP6 (phospho-Ser1490) rabbit pAb
Product Sizes
50UL
£ POA
ES15104-50UL
100UL
£ POA
ES15104-100UL
About this Product
- SKU:
- ES15104
- Additional Names:
- Low-density lipoprotein receptor-related protein 6 (LRP-6)
- Application:
- Western Blot, Immunohistochemistry
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or; with Frizzled; a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation; proliferation; and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq; Dec 2009];
- Immunogen:
- Synthesized phosho peptide around human LRP6 (Ser1490)
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
