NALP4 rabbit pAb
Product Sizes
50UL
£ POA
ES14568-50UL
100UL
£ POA
ES14568-100UL
About this Product
- SKU:
- ES14568
- Application:
- Western Blot, Immunohistochemistry
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs; such as NALP4; have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD); followed by a NACHT domain; a NACHT-associated domain (NAD); and a C-terminal leucine-rich repeat (LRR) region. The long NALP; NALP1 (MIM 606636); also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g.; CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al.; 2003 [PubMed 12563287]).[supplied by OMIM; Mar 2008];
- Immunogen:
- Synthesized peptide derived from human NALP4 AA range: 307-357
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
