NOD1 rabbit pAb
Product Sizes
50UL
£ POA
ES14472-50UL
100UL
£ POA
ES14472-100UL
About this Product
- SKU:
- ES14472
- Additional Names:
- Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4)
- Application:
- Western Blot
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD); a centrally located nucleotide-binding domain (NBD); and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling; LRRs participate in protein-protein interactions; and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described; but the full-length nature of these variants has not been determined. [provided by RefSeq; Oct 2009];
- Immunogen:
- Synthesized peptide derived from human NOD1 AA range: 290-340
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
