ERK 1/2 (phospho Tyr222/205) rabbit pAb
Product Sizes
50UL
£ POA
ES1441-50UL
100UL
£ POA
ES1441-100UL
About this Product
- SKU:
- ES1441
- Additional Names:
- MAPK1; ERK2; PRKM1; PRKM2; Mitogen-activated protein kinase 1; MAP kinase 1; MAPK 1; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2; MAPK3; ER
- Application:
- Immunofluorescence, Western Blot, Immunohistochemistry, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the MAP kinase family. MAP kinases; also known as extracellular signal-regulated kinases (ERKs); act as an integration point for multiple biochemical signals; and are involved in a wide variety of cellular processes such as proliferation; differentiation; transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation; this kinase translocates to the nucleus of the stimulated cells; where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein; but differing in the UTRs; have been reporte
- Immunogen:
- Synthesized phospho-peptide around the phosphorylation site of human ERK 1/2 (phospho Tyr222/205)
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
