KOR-1 (phospho Ser369) rabbit pAb
Product Sizes
50UL
£ POA
ES1427-50UL
100UL
£ POA
ES1427-100UL
About this Product
- SKU:
- ES1427
- Additional Names:
- OPRK1; OPRK; Kappa-type opioid receptor; K-OR-1; KOR-1
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Endogenous opioid peptides and opiates; like morphine; transmit their pharmacological effects through membrane bound opioid receptors. Pharmacological studies and molecular cloning have led to the identification of three different types of opioid receptor; mu-type; delta-type and kappa-type; also designated MOR-1; DOR-1 and KOR-1; respectively. MOR-1 is a receptor for beta-endorphin; DOR-1 is a receptor for enkephalins; and KOR-1 is a receptor for dynorphins.The three opioid receptor types are highly homologous and belong to the superfamily of G-protein-coupled receptors. Opioid receptors have been shown to modulate a range of brain functions; including instinctive behavior and emotions. This regulation is thought to involve the inhibition of neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance.
- Immunogen:
- The antiserum was produced against synthesized peptide derived from mouse KOR-1 around the phosphorylation site of Ser369. AA range:331-380
- Isotype:
- IgG
- Reactivities:
- Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
