PCDGH rabbit pAb
Product Sizes
50UL
£ POA
ES14217-50UL
100UL
£ POA
ES14217-100UL
About this Product
- SKU:
- ES14217
- Application:
- Western Blot, ELISA, Immunohistochemistry
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene is a member of the protocadherin gamma gene cluster; one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization; suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes; subfamily B contains 7 genes and 2 pseudogenes; and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large; variable region exons are followed by a constant region; containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region; which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq; Jul 2008];
- Immunogen:
- Synthesized peptide derived from human PCDGH AA range: 137-187
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
