PLCγ1 (phospho-Ser1248) rabbit pAb
Product Sizes
50UL
£ POA
ES14069-50UL
100UL
£ POA
ES14069-100UL
About this Product
- SKU:
- ES14069
- Additional Names:
- 1-phosphatidylinositol 4;5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1)
- Application:
- Western Blot, Immunohistochemistry
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene catalyzes the formation of inositol 1;4;5-trisphosphate and diacylglycerol from phosphatidylinositol 4;5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example; when activated by SRC; the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi; where it activates Ras. Also; this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq; Jul 2008];
- Immunogen:
- Synthesized phosho peptide around human PLCγ1 (Ser1248)
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
