PSB11 rabbit pAb
Product Sizes
50UL
£ POA
ES13889-50UL
100UL
£ POA
ES13889-100UL
About this Product
- SKU:
- ES13889
- Application:
- Western Blot, Immunohistochemistry
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Proteasomes generate peptides that are presented by major histocompatibility complex (MHC) I molecules to other cells of the immune system. Proteolysis is conducted by 20S proteasomes; complexes of 28 subunits arranged as a cylinder in 4 heteroheptameric rings: alpha-1 to -7; beta-1 to -7; beta-1 to -7; and alpha-1 to -7. The catalytic subunits are beta-1 (PSMB6; MIM 600307); beta-2 (PSMB7; MIM 604030); and beta-5 (PSMB5; MIM 600306). Three additional subunits; beta-1i (PSMB9; MIM 177045); beta-2i (PSMB10; MIM 176847); and beta-5i (PSMB8; MIM 177046); are induced by gamma-interferon (IFNG; MIM 147570) and are preferentially incorporated into proteasomes to make immunoproteasomes. PSMB11; or beta-5t; is a catalytic subunit expressed exclusively in cortical thymic epithelial cells (Murata et al.; 2007 [PubMed 17540904]).[supplied by OMIM; Mar 2008];
- Immunogen:
- Synthesized peptide derived from human PSB11 AA range: 62-112
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
