PSB3 rabbit pAb
Product Sizes
50UL
£ POA
ES13888-50UL
100UL
£ POA
ES13888-100UL
About this Product
- SKU:
- ES13888
- Application:
- Western Blot, Immunohistochemistry
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome; the immunoproteasome; is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family; also known as the T1B family; that is a 20S core beta subunit. The 26 S proteasome may be involved in trinucleotide repeat expansion; a phenomenon which is associated with many hereditary neurological diseases. Pseudogenes have been identified on chromosomes 2 and 12. Alternative splicing results in multiple transcript variants [provided by RefSeq; Sep 2013];
- Immunogen:
- Synthesized peptide derived from human PSB3 AA range: 41-91
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
