SPTA1 rabbit pAb
Product Sizes
50UL
£ POA
ES12973-50UL
100UL
£ POA
ES12973-100UL
About this Product
- SKU:
- ES12973
- Application:
- Western Blot
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton; and functions in the determination of cell shape; arrangement of transmembrane proteins; and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin; which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders; including elliptocytosis type 2; pyropoikilocytosis; and spherocytic hemolytic anemia. [provided by RefSeq; Jul 2008];
- Immunogen:
- Synthesized peptide derived from human SPTA1 AA range: 1217-1267
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
