SPTC3 rabbit pAb
Product Sizes
50UL
£ POA
ES12971-50UL
100UL
£ POA
ES12971-100UL
About this Product
- SKU:
- ES12971
- Application:
- Western Blot
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The SPTLC3 gene encodes an isoform of the third subunit of serine palmitoyltransferase (SPT; EC 2.3.1.50); which catalyzes the rate-limiting step of the de novo synthesis of sphingolipids (Hornemann et al.; 2006 [PubMed 17023427]). SPT contains 2 main subunits: the common SPTLC1 subunit (MIM 605712) and either SPTLC2 (MIM 605713) or its isoform SPTLC2L (SPTLC3); depending on the tissue in which biosynthesis occurs (Hornemann et al.; 2006 [PubMed 17023427]). There are also 2 highly related isoforms of a third subunit; SSSPTA (MIM 613540) and SSSPTB (MIM 610412); that confer acyl-CoA preference of the SPT enzyme and are essential for maximal enzyme activity (Han et al.; 2009 [PubMed 19416851]).[supplied by OMIM; Nov 2010];
- Immunogen:
- Synthesized peptide derived from human SPTC3 AA range: 341-391
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
