SPTN2 rabbit pAb
Product Sizes
50UL
£ POA
ES12970-50UL
100UL
£ POA
ES12970-100UL
About this Product
- SKU:
- ES12970
- Application:
- Western Blot, Immunohistochemistry
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2); is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to; but distinct from; the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia; SCA5; that is characterized by neurodegeneration; progressive locomotor incoordination; dysarthria; and uncoordinated eye movements. [provided by RefSeq; Dec 2009];
- Immunogen:
- Synthesized peptide derived from human SPTN2 AA range: 644-694
- Isotype:
- IgG
- Reactivities:
- Human, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
