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Antibodies

STRAB rabbit pAb

Product Sizes
50UL
£ POA
ES12900-50UL
100UL
£ POA
ES12900-100UL
About this Product
SKU:
ES12900
Application:
Western Blot
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered; and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11; a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm; and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein; and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes; located on chromosomes 1 and 7; have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq; May 2011];
Immunogen:
Synthesized peptide derived from human STRAB AA range: 313-363
Isotype:
IgG
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Type:
Antibodies: Polyclonal Antibody
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