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Antibodies

PTN21 rabbit pAb

Product Sizes
50UL
£ POA
ES11929-50UL
100UL
£ POA
ES11929-100UL
About this Product
SKU:
ES11929
Application:
Western Blot, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth; differentiation; mitotic cycle; and oncogenic transformation. This PTP contains an N-terminal domain; similar to cytoskeletal- associated proteins including band 4.1; ezrin; merlin; and radixin. This PTP was shown to specially interact with BMX/ETK; a member of Tec tyrosine kinase family characterized by a multimodular structures including PH; SH3; and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3; but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis. [provided by RefSeq; Jul 2008];
Immunogen:
Synthesized peptide derived from part region of human protein
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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