ILF2 rabbit pAb
Product Sizes
50UL
£ POA
ES11916-50UL
100UL
£ POA
ES11916-100UL
About this Product
- SKU:
- ES11916
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45; ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90; ILF3); and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm; to repair DNA breaks by nonhomologous end joining; and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth; possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14. [provided by RefSeq; Dec 2014];
- Immunogen:
- Synthesized peptide derived from part region of human protein
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
