IOD2 rabbit pAb
Product Sizes
50UL
£ POA
ES11834-50UL
100UL
£ POA
ES11834-100UL
About this Product
- SKU:
- ES11834
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- deiodinase; iodothyronine type II(DIO2) Homo sapiens The protein encoded by this gene belongs to the iodothyronine deiodinase family. It catalyzes the conversion of prohormone thyroxine (3;5;3';5'-tetraiodothyronine; T4) to the bioactive thyroid hormone (3;5;3'-triiodothyronine; T3) by outer ring 5'-deiodination. This gene is widely expressed; including in thyroid; placenta; pituitary and brain. It is thought to be responsible for the 'local' production of T3; and thus important in influencing thyroid hormone action in these tissues. It has also been reported to be highly expressed in thyroids of patients with Graves disease; and in follicular adenomas. The intrathyroidal T4 to T3 conversion by this enzyme may contribute significantly to the relative increase in thyroidal T3 production in these patients. This protein is a selenoprotein containing the rare selenocysteine (Sec) amino acid at its active site; and may
- Immunogen:
- Synthesized peptide derived from part region of human protein
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
